New Technologies Elevate Pancreatic Cyst Assessment

For the differentiation of pancreatic cystic lesions, newer approaches demonstrate more sensitivity and specificity than the standard of care and may be best used together, according to studies from Digestive Disease Week 2022.

Investigators found that application of advanced diagnostics such as endoscopic ultrasound-guided needle-based confocal laser endomicroscopy (EUS-nCLE) and next-generation sequencing (NGS) can improve lesion classification and patient management.

“[For] the management of pancreatic cystic lesions [PCLs] with at least one worrisome feature, the application of advanced diagnostics with endomicroscopy and [NGS] fully optimizes the classification of the lesions. Endoscopists need to consider these tests,” said investigator Somashekar G. Krishna, MD, a clinical professor of internal medicine at The Ohio State University Wexner Medical Center, in Columbus, who presented one of the studies.